书目名称 | Tumor Dormancy, Quiescence, and Senescence, Vol. 3 | 副标题 | Aging, Cancer, and N | 编辑 | M.A. Hayat | 视频video | | 概述 | Discusses the effects of senescence and dormancy in breast cancer, ovarian cancer and leukemia, as well as in cardiovascular diseases.Advances the body of knowledge of cancer cell regression, includin | 丛书名称 | Tumor Dormancy and Cellular Quiescence and Senescence | 图书封面 |  | 描述 | This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia prot | 出版日期 | Book 2014 | 关键词 | Cancer; Cancer Stem cells and dormancy; Cardiovascular disorders; Distant Metastases; Leukemia | 版次 | 1 | doi | https://doi.org/10.1007/978-94-017-9325-4 | isbn_softcover | 978-94-024-0807-2 | isbn_ebook | 978-94-017-9325-4 | copyright | Springer Science+Business Media Dordrecht 2014 |
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