| 书目名称 | Transmembrane Signaling Protocols | | 编辑 | Dafna Bar-Sagi | | 视频video | | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Progress within any scientific discipline rests firmly on the development of methodologies that afford new ways to address unsolved questions. In the past decade, the development and application of novel technologies and approaches for structure determination, biochemical characterization, and molecular manipulation of signaling molecules have resulted in remarkable progress in the understanding of signal transduction pathways. Thus, whereas not so long ago small molecules known as second messengers were the only identified mediators of transmembrane signals, it is now clear that many (per haps most) signal transduction pathways operate through complex networks of protein-protein interactions. In recognition of this central mechanism, Transmembrane Signaling Pro tocols is largely devoted to techniques that are widely used to study molecular crosstalk between signaling molecules. The two underlying goals of the chap ters assembled in this volume are: to offer technical information that allows reproduction of these methods and to provide the general principles on which these are based. In addition, introductory reviews have been included to fur nish a comprehensive overview of re | | 出版日期 | Book 19981st edition | | 版次 | 1 | | doi | https://doi.org/10.1385/0896034887 | | isbn_ebook | 978-1-59259-568-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 1998 |
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发表于 2025-3-21 18:40:18
