书目名称 | Transgenic Mouse Methods and Protocols |
编辑 | Marten H. Hofker,Jan Deursen |
视频video | |
概述 | Fully updated from the first edition to offer cutting-edge methods for generation of transgenic mouse models.Provides descriptions of how to generate conventional knockout and transgenic mice.Includes |
丛书名称 | Methods in Molecular Biology |
图书封面 |  |
描述 | The generation of genetically modified mice is absolutely crucial to gene function studies today, primarily because mice are genetically similar to man and because gene function studies in mice are in the context of a whole organism, making them particularly useful.In Transgenic Mouse Methods and Protocols, Second Edition, expert research explore current advances in the field through detailed laboratory protocols.Chapters provide a general introduction outlining how to deal with mice and how to generate transgenic mouse models, explore the generation of conditional and induced knockout and transgenic mice, and offer alternative routes to studying gene function in mice. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.Comprehensive and state of the art, Transgenic Mouse Methods and Protocols, second Edition is the ideal guide for all researchers interested in the latest information about the production and analysis of transgenic and knockout mice. |
出版日期 | Book 2011Latest edition |
关键词 | Gene function; Genotype-phenotype relationships; Knockout mice; Transgenic mice; Transgenic mouse models |
版次 | 2 |
doi | https://doi.org/10.1007/978-1-60761-974-1 |
isbn_softcover | 978-1-4939-5676-0 |
isbn_ebook | 978-1-60761-974-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
issn_series | 1064-3745 |
copyright | Springer Science + Business Media, LLC 2011 |