| 书目名称 | Towards a New Neuromorphology | | 编辑 | Rudolf Nieuwenhuys,Luis Puelles | | 视频video | | | 概述 | Presents and incorporates new molecular evidence concerning the fundamental processes of CNS development.Explains how the molecular and cellular events of early development are causally related to eme | | 图书封面 |  | | 描述 | .This book demonstrates that the systematic study of gene expression patterns in embryonic and adult brains, in combination with selected data from earlier studies, can pave the way for a new neuromorphology, the most salient features of which may be summarized as follows: (1) Causal analysis of molecular patterning at neural plate and early neural tube stages has shown that the CNS is essentially organized into transverse neural segments or neuromeres and longitudinal zones which follow the curved axis of the brain. (2) The FMUs initially represent thin neuroepithelial fields; in the course of further development they are transformed into three-dimensional radial units, extending from the ventricular surface to the meningeal surface of the brain. (3) The principal histogenetic processes, including cellular proliferation, cell migration and differentiation, essentially take place within the confines of these radial units, controlled by characteristic sets of developmental regulatory genes. (4) Although most developing neurons migrate radially and settle within their own FMU, at many locations neuroblasts leave the FMU where they were produced and migrate tangentially to other nearb | | 出版日期 | Book 2016 | | 关键词 | Fundamental morphological units; Neuromeres; Homology; Patterning; Neural genoarchitecture; Topology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-25693-1 | | isbn_softcover | 978-3-319-79829-5 | | isbn_ebook | 978-3-319-25693-1 | | copyright | Springer International Publishing Switzerland 2016 |
The information of publication is updating
|
|
发表于 2025-3-21 20:00:54
