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Titlebook: Topics in Topicals; Current Trends in th Ronald Marks Book 1985 MTP Press Limited 1985 absorption.cosmetics.development.drug.drugs.fat.infl

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The Clinical Relevance of , Investigations for Percutaneous Absorption,ament from the vehicle, followed by its penetration through the skin barriers and finally its activation of the desired pharmacological response. Effective topical therapy optimizes these processes as they are affected by three components — the drug, the vehicle and the skin..
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,Topical and Oral Preparations of Glyceryl Trinitrate — A Comparative Study,Organic nitrates such as glyceryl trinitrate (GTN) are available in several different dosage forms, e.g. sublingual, oral and topical. The requirement for so many pharmaceutical preparations stems mainly from the short-lived pharmacological effect of these compounds and the resultant attempts to prolong it.
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Pharmacological and Physical Measurement of Drug Penetration into Skin,The problem being addressed here may be stated as: ‘given a molecule with potential local activity in skin, how may the molecule be modified so as to maximize both its intrinsic pharmacological effect and its skin penetration ability?’
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978-94-010-8673-8MTP Press Limited 1985
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ds that have been presented in the literature since the late 1990’s. To the best knowledge of the author, these data-based design methods have never been collected in a single text, analyzed in depth or compared to each other, and this severely limits their widespread application. In this book these
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R. Marks analysis techniques are becoming critical tools for managing the increasingly complex concept improvement process. The advantages of the data-driven approach lie in its objectivity, as traditionally, design decisions depend on designers’ subjective opinions. This chapter introduces a data-driven ap
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