| 书目名称 | Toll-like Receptors in Inflammation |
| 编辑 | Luke A.J. O’Neill,Elizabeth Brint |
| 视频video | http://file.papertrans.cn/926/925850/925850.mp4 |
| 概述 | Written by leading scientists in the field.Covers the current understanding of TLRs and their role in inflammatory diseases.Gives outlook on the development of drugs.Includes supplementary material: |
| 丛书名称 | Progress in Inflammation Research |
| 图书封面 |  |
| 描述 | .A repertoire of 10 TLRs mediate the first response to all microbes that infect mammals. They are the long sought receptors for a wide range of microbial products. Notable examples include TLR4 which recognizes LPS from gram negative bacteria, TLR3 which recognizes viral double-stranded RNA and TLR9 which recognizes CpG DNA motifs, found commonly in both viruses and bacteria. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis and asthma. There is therefore great interest in targeting TLRs therapeutically since blocking TLRs will result in a decrease in the production of inflammatory mediators such as TNF. This volume covers our current understanding of TLRs, and their role in inflammation. Given the primacy of TLRs in the inflammatory process and their emerging role in inflammatory diseases the book is of great interest to researchers working in inflammation and immunology.. |
| 出版日期 | Book 2005 |
| 关键词 | Sepsis; asthma; autoimmune disease; bacteria; bacterial infection; cytokine; diseases; immunology; infection |
| 版次 | 1 |
| doi | https://doi.org/10.1007/3-7643-7441-1 |
| isbn_ebook | 978-3-7643-7441-9Series ISSN 1422-7746 Series E-ISSN 2296-4525 |
| issn_series | 1422-7746 |
| copyright | Birkhäuser Basel 2005 |
|Archiver|手机版|小黑屋|
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