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Titlebook: Toll-Like Receptor Family Members and Their Ligands; Bruce Beutler,Hermann Wagner Book 2002 The Editor(s) (if applicable) and The Author(s

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书目名称Toll-Like Receptor Family Members and Their Ligands
编辑Bruce Beutler,Hermann Wagner
视频video
概述First book describing the sensing mechanism of the innate immune system..Includes supplementary material:
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: Toll-Like Receptor Family Members and Their Ligands;  Bruce Beutler,Hermann Wagner Book 2002 The Editor(s) (if applicable) and The Author(s
描述On occasion, the innate immune system is referred to as the "primitive" immune system. Perhaps this has dissuaded immu­ nologists from analyzing it as energetically as they have analyzed the adaptive immune system during the past two decades. But while its phylogenetic origins are indeed ancient, and though it is "of the first type", there is nothing crude, nothing unsophisti­ cated, and nothing "inferior" about innate immunity. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due. Any immune system has two cardinal functions. It must destroy a broad range of pathogens, and it must spare the host. The adaptive immune system has applied a modular solution to these problems. Each cell of the adaptive immune system is prescreened to eliminate those that would produce untoward interactions with self; each cell is pre-programmed to recognize a foreign epitope that the host might one day encounter. Hence, the duties of each individual lymphocyte are quite circumscribed.
出版日期Book 2002
关键词Innate immune system; bacteria; granulocyte; immune response; immune system; immunity; innate immunity; lym
版次1
doihttps://doi.org/10.1007/978-3-642-59430-4
isbn_softcover978-3-642-63975-3
isbn_ebook978-3-642-59430-4Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
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