| 书目名称 | Thymic Development and Selection of T Lymphocytes |
| 编辑 | Thomas Boehm,Yousuke Takahama |
| 视频video | |
| 概述 | Written by leading experts in the field.Addresses key aspects of the process of thymopoiesis.Offers perspectives for understanding immunodeficiency and autoimmune diseases.Includes supplementary mater |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | .The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.. |
| 出版日期 | Book 2014 |
| 关键词 | Adaptive immunity; Autoimmunity; Cellular immunity; Immunodeficiency; Thymus function; cytogenetics |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-40252-4 |
| isbn_softcover | 978-3-662-51196-1 |
| isbn_ebook | 978-3-642-40252-4Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
发表于 2025-3-21 19:39:26
