书目名称 | Therapeutic potential of Cell Cycle Kinases in Breast Cancer |
编辑 | Manzoor Mir |
视频video | http://file.papertrans.cn/925/924148/924148.mp4 |
概述 | Discusses role of Cyclin-Dependent Kinases (CDK) in breast cancer progression and treatment.Reviews CDKs as promising target for cancer therapy.Examines clinical role of CDK 4/6 inhibitors in metastat |
图书封面 |  |
描述 | This book highlights the interrelation between cell cycle regulators and breast cancer phenotypes. It reviews the roles of Cyclin-Dependent Kinases (CDK) in driving cell cycle progression, cell cycle checkpoints and dysregulation in breast cancer. It also examines the prognostic significance of CDKs in breast cancer. and CDK inhibitors for the treatment of metastatic breast cancer. Further, the book discusses the role of different G1 cyclins in differentiation, chromosome stability, and transcriptional regulation in breast cancer. Additionally, it examines the role of immunogenic effects of CDK inhibitors, the mechanism of resistance and the current clinical trials in breast cancer treatment. Towards the end, the book explores cell cycle regulation as an attractive target for targeted drug therapy in breast cancer. This book is a comprehensive yet concise resource for oncologists and researchers interested in exploring the therapeutic potential of Cyclin-Dependent Kinases in breast cancer.. |
出版日期 | Book 2023 |
关键词 | Breast Cancer; Cell cycle; Cyclin Dependent Kinases; CDK Inhibitors; Targeted therapy |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-19-8911-7 |
isbn_softcover | 978-981-19-8913-1 |
isbn_ebook | 978-981-19-8911-7 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor |