| 书目名称 | Therapeutic Enzymes: Function and Clinical Implications |
| 编辑 | Nikolaos Labrou |
| 视频video | |
| 概述 | Incorporates a wealth of research that clarifies several aspects of the development and application of therapeutic enzymes.Equips readers with a comprehensive understanding of enzyme-based therapeutic |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Therapeutic enzymes exhibit fascinating features and opportunities, and represent a significant and promising subcategory of modern biopharmaceuticals for the treatment of several severe diseases. Research and drug developments efforts and the advancements in biotechnology over the past twenty years have greatly assisted the introduction of efficient and safe enzyme-based therapies for a range of both rare and common disorders. The introduction and regulatory approval of twenty different recombinant enzymes has enabled effective enzyme-replacement therapy. This volume aims to overview these therapeutic enzymes, focusing in particular on more recently approved enzymes produced by recombinant DNA technology. This volume is composed of four sections. Section 1 provides an overview of the production process and biochemical characterization of therapeutic enzymes, while Section 2 focuses upon the engineering strategies and delivery methods of therapeutic enzymes. Section 3 highlights the clinical applications of approved therapeutic enzymes, including aspects on their structure, indications and mechanisms of action. Together with information on these mechanisms, safety and immunogenicit |
| 出版日期 | Book 2019 |
| 关键词 | Therapeutic Enzymes; Recombinant Enzymes; Protein Engineering; Enzyme Therapy; Enzyme Manufacturing |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-13-7709-9 |
| isbn_softcover | 978-981-13-7711-2 |
| isbn_ebook | 978-981-13-7709-9Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | Springer Nature Singapore Pte Ltd. 2019 |
发表于 2025-3-21 17:30:45
