书目名称 | Therapeutic Angiogenesis |
编辑 | J. A. Dormandy,W. P. Dole,G. M. Rubanyi |
视频video | |
概述 | First book on Therapeutic Angiogenesis.First book on Angiogenic Gene Therapy.First book to review better basic science and clinical applications of Therapeutic Angiogenesis |
丛书名称 | Ernst Schering Foundation Symposium Proceedings |
图书封面 |  |
描述 | Over the past decade, rapid progress had been made in elucidating the cellular and molecular mechanisms of new blood vessel formation in both health and disease. Lack of sufficient angiogenesis (new capillary development) and collateral formation (remodeling of existing blood vessels) in adult tissues (e. g. , heart, brain, skeletal muscle) during criti cal ischemia has prompted novel therapeutic strategies to stimulate/fa cilitate angiogenesis and collateral formation in ischemic conditions ("therapeutic angiogenesis"). Therapeutic angiogenesis describes a strategy of inducing new col lateral vessels that can bypass vascular obstructions caused by atherosclerotic disease and stimulating new capillaries that can en hance tissue oxygen exchange. Naturally occurring growth factors (e. g. , FGFs, VEGFs) have been identified and demonstrated to induce new blood vessel formation in the adult organism. The therapeutic ap plication of these growth factors has been demonstrated to enhance these natural processes and have been shown in a number of animal models to increase blood flow and oxygen exchange to ischemic tis sues. Therapeutic angiogenesis therefore represents a new medical |
出版日期 | Conference proceedings 1999 |
关键词 | Angiogenic; Growth Factors; Protein Therapy; Transmyocardial Laser; angiogenesis; artery; cardiovascular; c |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-662-03776-8 |
isbn_softcover | 978-3-662-03778-2 |
isbn_ebook | 978-3-662-03776-8Series ISSN 0947-6075 |
issn_series | 0947-6075 |
copyright | Springer-Verlag Berlin Heidelberg 1999 |