书目名称 | The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions | 编辑 | William J. Meggs | 视频video | | 概述 | Summarizes current understand of the role of respiratory irritants in inducing and exacerbating asthma, rhinitis, and related conditions.Constitutes essential reading for researching investigating che | 图书封面 |  | 描述 | .Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals..This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intole | 出版日期 | Book 2013 | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4614-9044-9 | isbn_softcover | 978-1-4899-7949-0 | isbn_ebook | 978-1-4614-9044-9 | copyright | Springer Science+Business Media, LLC 2013 |
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