| 书目名称 | The Sodium Pump | | 副标题 | Structure Mechanism, | | 编辑 | Ernst Bamberg,Wilhelm Schoner | | 视频video | http://file.papertrans.cn/921/920023/920023.mp4 | | 图书封面 |  | | 描述 | The sodium of animal cell membranes converts the chemical energy obtained from the hydrolysis of adenosine 5‘ -triphosphate into a movement of the cations Na + and K + against an electrochemical gradient. The gradient is used subse quently as an energy source to drive the uptake of metabolic substrates in polar epithelial cells and to use it for purposes of communications in excitable cells. The biological importance of the sodium pump is evident from the fact that be tween 20-70% of the cell‘s metabolic energy is consumed for the pumping pro cess. Moreover, the sodium pump is an important biological system involved in regulatory processes like the maintenance of the cells‘ and organism‘s water me tabolism. It is therefore understandable that special cellular demands are han dled better by special isoforms of the sodium pump, that the expression of the sodium pump and their isoforms is regulated by hormones as is the activity of the sodium pump via hormone-regulated protein kinases. Additionally, the sodium pump itself seems to be a receptor for a putative new group of hormones, the endogenous digitalis-like substances, which still have to be defined in most cases in their str | | 出版日期 | Book 1994 | | 关键词 | Alanin; Calcium; Nucleotide; amino acid; biology; cell biology; cell membrane; cells; enzyme; enzymes; gene ex | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-72511-1 | | isbn_softcover | 978-3-642-72513-5 | | isbn_ebook | 978-3-642-72511-1 | | copyright | Dietrich Steinkopff Verlag GmbH & Co. KG, Darmstadt 1994 |
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