书目名称 | The Serotonin Receptors | 编辑 | Elaine Sanders-Bush | 视频video | | 丛书名称 | The Receptors | 图书封面 |  | 描述 | Serotonin (5-HT) was isolated and chemically characterized nearly four decades ago, and is now generally accepted to function as a neurotransmitter and neuromodulatory agent. Early research focused on the measurement of concentrations, synthesis, and metabolism of 5-HT, and only recently has the focus shifted to characterization of 5-HT receptors. Gaddum and Picarelli first sug gested in 1957 that the effect of 5-HT in the guinea pig ileum is mediated by two pharmacologically distinguishable receptors; however, the possibility of dual5-HT receptors was not explored systematically or successfully until the past decade. It is now clear that more, perhaps many more, subclasses of 5-HT receptors exist. The purpose of this book is to provide an up-to-date report on 5-HT receptors. This is a difficult task considering the astonishing speed at which research in this field is expanding. As the first of what we can expect to be a steady stream of monographs focusing on 5-HT receptors, the book confirms that we are in an exciting time in the history of 5-HT. For those of us who have been work ing on 5-HT for many years, our dream of equal progress and recognition with the more extensively | 出版日期 | Book 1988 | 关键词 | Nervous System; Vivo; biochemistry; catecholamines; cognition; cortex; metabolism; neurotransmitter; pharmac | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4612-4560-5 | isbn_softcover | 978-1-4612-8912-8 | isbn_ebook | 978-1-4612-4560-5Series ISSN 1048-6909 Series E-ISSN 2524-6488 | issn_series | 1048-6909 | copyright | The Humana Press Inc. 1988 |
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