| 书目名称 | The Role of Glycosylation in Health and Disease |
| 编辑 | Gordan Lauc,Irena Trbojević-Akmačić |
| 视频video | |
| 概述 | Illustrates the importance and function of different types of glycosylation in humans, written by experts in the field.Reviews the role of glycosylation process in the pathophysiology of different dis |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research..Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans..The Role of Glycosylation in Health and Disease provides a comprehensive overview of types an |
| 出版日期 | Book 2021 |
| 关键词 | Aberrant glycosylation; Biomarker research; Critical quality attribute; Glycan biosynthesis; Glycan func |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-70115-4 |
| isbn_softcover | 978-3-030-70117-8 |
| isbn_ebook | 978-3-030-70115-4Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 19:21:00
