书目名称 | The Orexin/Hypocretin System | 副标题 | Physiology and Patho | 编辑 | Seiji Nishino,Takeshi Sakurai | 视频video | http://file.papertrans.cn/916/915306/915306.mp4 | 概述 | Includes supplementary material: | 丛书名称 | Contemporary Clinical Neuroscience | 图书封面 |  | 描述 | Impairment of orexin/hypocretin signaling causes narcolepsy-cataplexy in animals and humans.Most human narcolepsy-cataplexy cases are associated with orexin/hypocretin ligand deficiency, which can be detected clinically using cerebrospinal orexin/hypocretin measures and may lead to future treatments with orexin/hypocretin replacement therapy. In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians review these exciting developments to set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation.Topics of interest include an assessment of the functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible pharmacological treatments. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations..Authoritative and state-of-the-art, The Orexin/Hyp | 出版日期 | Book 2005 | 关键词 | Nervous System; biological fluid; clinical application; neuroendocrinology; neurons; pathophysiology; phys | 版次 | 1 | doi | https://doi.org/10.1385/1592599508 | isbn_softcover | 978-1-61737-574-3 | isbn_ebook | 978-1-59259-950-9Series ISSN 2627-535X Series E-ISSN 2627-5341 | issn_series | 2627-535X | copyright | Humana Press 2005 |
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