| 书目名称 | The Optical Clearing Method |
| 副标题 | A New Tool for Clini |
| 编辑 | Luís Manuel Couto Oliveira,Valery Victorovich Tuch |
| 视频video | |
| 概述 | Describes the optical method for obtaining drug diffusion properties in biological tissues.Discusses cryoprotective properties of optical clearing agents |
| 丛书名称 | SpringerBriefs in Physics |
| 图书封面 |  |
| 描述 | This book describes the Optical Immersion Clearing method and its application to acquire information with importance for clinical practice and various fields of biomedical engineering. The method has proved to be a reliable means of increasing tissue transparency, allowing the investigator or surgeon to reach deeper tissue layers for improved imaging and laser surgery. This result is obtained by partial replacement of tissue water with an active optical clearing agent (OCA) that has a higher refractive index and is a better match for the refractive index of other tissue components. Natural tissue scattering is thereby reduced. An exponential increase in research using this method has occurred in recent years, and new applications have emerged, both in clinical practice and in some areas of biomedical engineering. Recent research has revealed that treating ex vivo tissues with solutions containing active OCAs in different concentrations produces experimental data to characterize drug delivery or to discriminate between normal and pathological tissues. The obtained drug diffusion properties are of interest for the pharmaceutical and organ preservation industry. Similar data can be es |
| 出版日期 | Book 2019 |
| 关键词 | Optical Immersion Clearing method; Optical Clearing Agents; Optical Clearing mechanisms; Measurements d |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-33055-2 |
| isbn_softcover | 978-3-030-33054-5 |
| isbn_ebook | 978-3-030-33055-2Series ISSN 2191-5423 Series E-ISSN 2191-5431 |
| issn_series | 2191-5423 |
| copyright | The Author(s), under exclusive license to Springer Nature Switzerland AG 2019 |
发表于 2025-3-21 16:13:03
