| 书目名称 | The Mitotic Exit Network | | 副标题 | Methods and Protocol | | 编辑 | Fernando Monje-Casas,Ethel Queralt | | 视频video | | | 概述 | Includes cutting-edge methods and protocols for studying the Mitotic Exit Network.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | This detailed book collects the main methodologies used for the analysis of the activity, localization, and regulation of the components of the Mitotic Exit Network (MEN) pathway during mitotic exit in .Saccharomyces cerevisiae., as well as for the evaluation of the roles of these proteins in other cellular processes, such as the condensation of the rDNA, the functionality of the mitotic checkpoints, and cytokinesis. Budding yeast serves as an ideal model system for dissecting the mechanisms that regulate cell cycle progression and providing new insights into the molecular basis of cell cycle control and, thus, into the origin of diseases that arise as a consequence of problems during cell division. Therefore, although this volume concentrates on .Saccharomyces cerevisiae. as a model, it also details the implications that the research about the MEN have on our understanding of the mitotic exit process in higher eukaryotes. Written for the highly successful .Methods inMolecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting | | 出版日期 | Book 2017 | | 关键词 | Yeast models; MEN pathway; Saccharomyces cerevisiae; Cell cycle progression; MEN component localization; | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-6502-1 | | isbn_softcover | 978-1-4939-8220-2 | | isbn_ebook | 978-1-4939-6502-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media New York 2017 |
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发表于 2025-3-21 19:18:51
