书目名称 | The Mast Cell | 副标题 | A Multifunctional Ef | 编辑 | Domenico Ribatti | 视频video | | 概述 | This book contains a comprehensive and updated view of Mast Cell Biology.Broadens the understanding of Mast Cells from their classic immunological role to include their role in human health homeostasi | 图书封面 |  | 描述 | Mast cells (MC) are phylogenetically old cells which are distributed throughout the human organism. MC are found in almost all of the major organs and tissues of the body, particularly in association with connective tissue structures such as blood vessels, lymphatic vessels and nerves, and in proximity to surfaces that interface the external environment, such as those of the respiratory and gastrointestinal system and the skin. This selective accumulation at tissue sites where foreign material attempts to invade the host suggests that MC are among the first cells to initiate defensive mechanisms. MC have long been recognized as key cells of type I hypersensitivity reactions. Several lines of evidence, however, indicate that they not only express critical effector functions in classic IgE-associated allergic disorders, but also play important roles in host defense against parasites, bacteria and perhaps even viruses. Indeed, it is now clear that MC can contribute to host defense in thecontext of either acquired or innate immune responses through the release of a myriad of pro-inflammatory and immunoregulatory molecules and the expression of a wide spectrum of surface receptors for c | 出版日期 | Book 2019 | 关键词 | Angiogenesis; Basophils; Mast cell; Tumor growth; Vascultitides | 版次 | 1 | doi | https://doi.org/10.1007/978-3-030-24190-2 | isbn_softcover | 978-3-030-24192-6 | isbn_ebook | 978-3-030-24190-2 | copyright | Springer Nature Switzerland AG 2019 |
The information of publication is updating
|
|