| 书目名称 | The Kinetochore: | | 副标题 | From Molecular Disco | | 编辑 | Peter De Wulf,William C. Earnshaw | | 视频video | | | 概述 | Ties together the latest research into the workings of the kinetochore/centromere complex and neocentromeres; including what is known about their structure, how they function, how they are regulated,. | | 图书封面 |  | | 描述 | .Kinetochores orchestrate the faithful transmission of chromosomes from one generation to the next. Kinetochores were first depicted over 100 years ago, but kinetochore research has progressed by leaps and bounds since the first description of their constituent DNA and proteins in the 1980s. “.The Kinetochore: from Molecular Discoveries to Cancer Therapy” .presents a thorough up-to-date analysis of kinetochore and centromere composition, formation, regulation, and activity, both in mitosis and meiosis, in humans and “model” eukaryotic species, and at natural and mutant neocentromeres. Recently initiated translational research on kinetochores is also discussed as kinetochores are being mined as a very rich target for the next generations of anti-cancer drugs.. | | 出版日期 | Book 2009 | | 关键词 | Chromosom; DNA; Evolution; cell division; cytokinesis; eukaryotic chromosome; functional analysis; kinetoch | | 版次 | 1 | | doi | https://doi.org/10.1007/978-0-387-69076-6 | | isbn_softcover | 978-1-4419-2398-1 | | isbn_ebook | 978-0-387-69076-6 | | copyright | Springer-Verlag New York 2009 |
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发表于 2025-3-21 19:10:52
