书目名称 | The Hypothalamic-Pituitary-Adrenal Axis in Health and Disease | 副标题 | Cushing’s Syndrome a | 编辑 | Eliza B. Geer | 视频video | | 概述 | Explores recent advances in the development of novel medical therapies for the treatment of Cushing’s syndrome.Provides valuable and cutting edge perspectives on these topics including the concept of | 图书封面 |  | 描述 | Cushing´ssyndrome is a rare disorder that is associated with many co-morbiditiessuch as systemic hypertension, diabetes, osteoporosis, impaired immunefunction, and psychiatric disease, allof which severely reduce quality of life and life expectancy. This bookreviews the role of cortisol in the human body, focusing on the effectsof excess cortisol dueto Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function.The volume will cover basic mechanistic data, clinical outcomes data,and novel therapies. Also discussed are everything from abnormalities ofthe HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders andmetabolic disorders, to new definitions of Cushing’s remission andrecurrence. The Hypothalamic Pituitary Adrenal Axis in Health andDisease will provide a comprehensive and multi-disciplinary review ofthe pathophysiology and outcomes of excess cortisol inthe human body and brain as well as the role of the HPA axis in otherdisease states. | 出版日期 | Book 2017 | 关键词 | HPA axis; adrenal; cortisol; metabolic disorders; neuroendocrine; pathophysiology; Systems Biology | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-45950-9 | isbn_softcover | 978-3-319-83405-4 | isbn_ebook | 978-3-319-45950-9 | copyright | Springer International Publishing Switzerland 2017 |
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