| 书目名称 | The Future of HIV-1 Therapeutics |
| 副标题 | Resistance Is Futile |
| 编辑 | Bruce E. Torbett,David S. Goodsell,Douglas D. Rich |
| 视频video | http://file.papertrans.cn/911/910160/910160.mp4 |
| 概述 | Highlights the identification and evaluation of antiretrovirals that may be less prone in selecting for HIV-1 resistance.Covers recent advances in the identification and function of small molecule inh |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | .This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.. |
| 出版日期 | Book 2015 |
| 关键词 | Fragment-based drug design; HIV Gag protein; HIV capsid; HIV integrase protein; HIV matrix; HIV nucleocap |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-18518-7 |
| isbn_softcover | 978-3-319-37450-5 |
| isbn_ebook | 978-3-319-18518-7Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | This is a U.S. Government work and not under copyright protection in the U.S.; foreign copyright pro |
|Archiver|手机版|小黑屋|
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