| 书目名称 | The Functional Nucleus | | 编辑 | David P. Bazett-Jones,Graham Dellaire | | 视频video | | | 概述 | Provides a state-of-the-art review on nuclear structure and functions.Highlights the relation between epigenomics and nuclear architecture.Gives an outlook on possible medical applications | | 图书封面 |  | | 描述 | .This book gives an in-depth overview on nuclear structure and function. Itclearly shows that the epigenome and the three-dimensional organization of thenucleus are not independent properties. The intimate relationship between thelocation and the epigenetic modifications of gene loci is highlighted. Finally,it shows that the complex three-dimensional organization of the nucleus is notjust of academic interest: The structure, composition and function of virtuallyall of the sub-nuclear compartments identified so far can be implicated to alist of human genetic diseases. Hence, a detailed elucidation of how thesedomains are assembled and function will provide new opportunities fortherapeutic intervention in clinical practice.. | | 出版日期 | Book 2016 | | 关键词 | Chromosomes; Epigenetics; Nuclear function; Nuclear regulation; Nuclear structure; Nucleus; cytogenetics | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-38882-3 | | isbn_softcover | 978-3-319-81768-2 | | isbn_ebook | 978-3-319-38882-3 | | copyright | Springer International Publishing Switzerland 2016 |
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发表于 2025-3-21 16:21:37
