书目名称 | The Extracellular Matrix and the Tumor Microenvironment |
编辑 | Ilona Kovalszky,Marco Franchi,Laura D. Alaniz |
视频video | |
概述 | Provides an overview of the major ECM components that are deregulated in cancer.Discusses the critical role of the ECM in tumoral angiogenesis.Elucidates how the ECM influences the success of immuno- |
丛书名称 | Biology of Extracellular Matrix |
图书封面 |  |
描述 | .This book introduces the most important and best studied extracellular and pericellular molecules of the tumor microenvironment. It gives a comprehensive overview of their role in tumor development and cancer progression..Twelve chapters deal with the biochemical and biophysical background of extracellular matrix (ECM) changes in the tumor stroma compared to the physiological state. The reader learns about the major ECM components that are deregulated during cancer development and how they are associated with cancer progression associated with survival, inflammation process, among others. These are followed by recent data about the cooperative activity of extracellular matrix in tumor metabolism, promoting cancer progression..Two chapters focus specifically on the critical role of the ECM in tumor angiogenesis, linking this process to cellular infiltration and metastatic behavior of tumors.. The final part describes how the ECM influences the success of immuno- and chemotherapy in cancer patients, its potential as biomarkers for diagnosis, prognosis, and therapeutic target, as well as the mechanism of resistance-associated changes in the ECM. .This book is an interesting read fo |
出版日期 | Book 2022 |
关键词 | Extracellular Matrix; Tumor Microenvironment; Proteoglycans; Glycosaminoglycans; Stemness; Angiogenesis; T |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-030-99708-3 |
isbn_softcover | 978-3-030-99710-6 |
isbn_ebook | 978-3-030-99708-3Series ISSN 0887-3224 Series E-ISSN 2191-1959 |
issn_series | 0887-3224 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |