书目名称 | The Centrosome and its Functions and Dysfunctions | 编辑 | Heide Schatten | 视频video | | 概述 | Sheds light on new aspects in centrosome functions.Discusses centrosomes significant impact on cellular functions and dysfunctions.Provides a valuable resource for newcomers and experts in the field | 丛书名称 | Advances in Anatomy, Embryology and Cell Biology | 图书封面 |  | 描述 | .The book provides a comprehensive overview of classic and modern approaches of centrosome research, including new aspects of centrosome functions focusing on primary cilia and their implications in numerous diseases. In addition, several chapters raise awareness of centrosomes in areas that have not yet fully considered the centrosome as an organelle that impacts other organelle functions directly or indirectly. It further relates centrosome functions to other research areas such as aging and stem cell research. ..Since its discovery almost 150 years ago the centrosome is increasingly being recognized as a most impactful organelle for its role, not only as primary microtubule organizing center (MTOC) but also as a major communication center for signal transduction pathways and as a center for proteolytic activities. Its significance for cell cycle regulation has been well studied and we now also know that centrosome dysfunctions are implicated in numerous diseases and disorders including cancer, cystic diseases of the kidney, liver fibrosis, cardiac defects, obesity and several other diseases and disorders...This new volume reviews the latest advances in the field and provides val | 出版日期 | Book 2022 | 关键词 | Microtubulus; Cytoskeleton; Cilia; Reproduction; Aging; Cancer | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-20848-5 | isbn_softcover | 978-3-031-20847-8 | isbn_ebook | 978-3-031-20848-5Series ISSN 0301-5556 Series E-ISSN 2192-7065 | issn_series | 0301-5556 | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
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