书目名称 | Textbook of Cell Signalling in Cancer | 副标题 | An Educational Appro | 编辑 | Jacques Robert | 视频video | | 概述 | Presents basic information on cell signalling pathways and their alterations in cancer.Designed for students, established oncologists and pharmaceutical industry R&D departments.A unique tool for trai | 图书封面 |  | 描述 | .This book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis..This comprehensive reference text is based on the master’s courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be. .used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alte | 出版日期 | Book 2015 | 关键词 | cancer; cell cycle; cell proliferation; oncology; signaling pathways | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-14340-8 | isbn_softcover | 978-3-319-34571-0 | isbn_ebook | 978-3-319-14340-8 | copyright | Springer International Publishing Switzerland 2015 |
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