书目名称 | Techniques and Methodological Approaches in Breast Cancer Research | 编辑 | Jose Russo,Irma H. Russo | 视频video | http://file.papertrans.cn/902/901553/901553.mp4 | 概述 | Explores various cutting-edge methodologies used in breast cancer research, including stem cell separation, molecular analysis of gene function and more.Explores imaging techniques that are integral f | 图书封面 |  | 描述 | This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research. The authors critically evaluate of the advantages and disadvantages of current methodologies, starting with the tools available for understanding the architecture of the human breast, including its tissue and cellular composition. The volume discusses the importance of functional studies in breast cancer research, especially with the help of laser capture microdissection, which allows the separation of small amounts of tissue, as well as specific cells, for biochemical analysis. In addition, the authors address methodologies including stem cell separation, which has helped in significantly understanding their role in normal breast development, but also further the understanding of breast cancer and its therapeutic management. The use of in vitro techniques and established cell lines for mechanistic studies in chemotherapeutic approaches have been invaluable will be discussed. Imaging techniques for evaluating in vitro and in vivo behavior of normal and cancerous breast tissue will be explored, as it provides a better understanding of the physiopathology of canc | 出版日期 | Book 2014 | 关键词 | breast cancer; epigenetics; proteomics; stem cells; transcriptome; gene expression | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-0718-2 | isbn_softcover | 978-1-4939-4662-4 | isbn_ebook | 978-1-4939-0718-2 | copyright | Springer Science+Business Media New York 2014 |
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