| 书目名称 | Targeting the DNA Damage Response for Cancer Therapy |
| 编辑 | Timothy A. Yap,Geoffrey I. Shapiro |
| 视频video | |
| 概述 | Features detailed information on the latest translational studies on PARP inhibitors.Contains ‘key points‘ and ‘expert opinion points‘ sections in each chapter for greater emphasis.Provides detailed i |
| 丛书名称 | Cancer Treatment and Research |
| 图书封面 |  |
| 描述 | This book discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic..Targeting the DNA Damage Response for Cancer Therapy .comprehensively reviews the application of PARP and other DDR inhibitors across oncology disciplines. Therefore, it is a valuable resource for all medical professionals and researchers who use or who are researching the use of these inhibitors on a day-to-day basis.. |
| 出版日期 | Book 2023 |
| 关键词 | DNA repair pathways; PARP trapping; Inhibition; Resistance mechanisms; Homologous recombination; Castrati |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-031-30065-3 |
| isbn_softcover | 978-3-031-30067-7 |
| isbn_ebook | 978-3-031-30065-3Series ISSN 0927-3042 Series E-ISSN 2509-8497 |
| issn_series | 0927-3042 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 19:33:20
