书目名称 | Targeting Lysine Demethylases in Cancer and Other Human Diseases |
编辑 | Qin Yan |
视频video | |
概述 | Reviews our knowledge on lysine demethylases.Provides insights into the therapeutic strategies targeting demethylases.Offers a perspective for future discoveries in biology |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | This book provides a comprehensive summary of our current knowledge on lysine demethylases, a class of epigenetic regulators. It takes the reader on an exciting journey spanning the past two decades, starting from the initial discovery and characterization of these enzymes and leading up to the development of their small molecule modulators. These modulators have shown promise in clinical trials and hold great potential to improve patient outcomes. The book captures the progress made in this field and highlights the significant advancements that have paved the way for potential therapeutic applications..The book covers a wide range of topics, spanning both basic biology and clinical implications associated with lysine demethylases. It offers a comprehensive historical and conceptual framework for the discovery and characterization of similar epigenetic enzymes or modulators. Chapter one serves as an introductory overview, providing insights into the general characteristics and functions of lysine demethylases. In subsequent chapters, specifically chapters two to eight, each major family of lysine demethylases is individually explored in depth. By providing in-depth insights into th |
出版日期 | Book 2023 |
关键词 | Lysine demethylases; lysine methyltransferases; KDMs; KMTs; lysine methylation; inflammation; cancer treat |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-031-38176-8 |
isbn_softcover | 978-3-031-38178-2 |
isbn_ebook | 978-3-031-38176-8Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |