书目名称 | Targeted Radionuclide Tumor Therapy |
副标题 | Biological Aspects |
编辑 | Torgny Stigbrand,Jörgen Carlsson,Gregory P. Adams |
视频video | |
概述 | Focus on biological effects of targeted radionuclide therapy.Comprehensive presentation of different mechanisms of tumor cell death.Up-to-date presentation of new targeting agents.Summaries of present |
图书封面 |  |
描述 | The last three decades have provided opportunities to explore the potential of treating malignant diseases with antibodies or other targeting molecules labelled with nuclides. While considerable advances have been reported, there is still a signi- cant amount of work left to accomplish before our ambitions can be achieved. It now seems timely to review the accomplishments achieved to date and to clarify the challenges that remain. The choice of radionuclide, the conjugation p- cedure employed, and the selection of suitable targets were early issues that were faced by our field that still persist, however we can now tackle these obstacles with significantly better insight. The expanding array of new targeting molecules (recombinant antibodies, peptides and agents based upon alternate scaffolds) may increase the therapeutic efficacy or even modify the radiation sensitivity of the targeted tumor cell. The title of this book “Targeted Radionuclide Tumour Therapy – Biological Aspects” was selected to reinforce the concept that a major focus of this volume was devoted to understanding the biological effects of targeting and radiation. These important issues have not previously been the p |
出版日期 | Book 2008 |
关键词 | Cancer Treatment; Cure vs Palliation; Monoclonal Antibodies; Radioimmunotherapy; Targeted Tumor Therapy; |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4020-8696-0 |
isbn_softcover | 978-90-481-7956-5 |
isbn_ebook | 978-1-4020-8696-0 |
copyright | Springer Science+Business Media B.V. 2008 |