| 书目名称 | Targeted Intracellular Drug Delivery by Receptor Mediated Endocytosis |
| 编辑 | Padma V. Devarajan,Prajakta Dandekar,Anisha A. D‘S |
| 视频video | |
| 概述 | Unique in that this is the first book focused on one aspect of intracellular delivery that focuses on cancer and infectious diseases.Essential advanced reference on receptor and receptor-mediated drug |
| 丛书名称 | AAPS Advances in the Pharmaceutical Sciences Series |
| 图书封面 |  |
| 描述 | This book elaborates on drug delivery targeting via intracellular delivery, specifically through the Receptor Mediated Endocytosis (RME) approach, due to the involvement of cellular receptors in various grave diseases. Targeted delivery relies on two basic approaches, passive and active targeting. While passive targeting approaches have shown great promise, the improved selectivity achieved with active targeting approaches has resulted in significantly higher efficacy. Interestingly there are numerous strategies for active targeting, many of which are already highlighted in , .Targeted Drug Delivery: Concepts and Applications.. Nevertheless an exciting and practical strategy for active targeting, which could enable high intracellular delivery, is through exploitation of RME. Cells in the body express receptors to enable various physiological and biochemical processes. As a result, many of these receptors are overexpressed in pathological conditions, or newer receptors expressed due to defective cellular functioning. RME is based on exploitation of such receptors to achieve intracellular delivery. While targeted delivery can have manifold applications, in this book we focus on two m |
| 出版日期 | Book 2019 |
| 关键词 | RME approach; cancer therapy; substrate ligand binding; cellular internalization by receptors; infectiou |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-030-29168-6 |
| isbn_ebook | 978-3-030-29168-6Series ISSN 2210-7371 Series E-ISSN 2210-738X |
| issn_series | 2210-7371 |
| copyright | American Association of Pharmaceutical Scientists 2019 |
发表于 2025-3-21 18:55:20
