书目名称 | Target Identification and Validation in Drug Discovery | 副标题 | Methods and Protocol | 编辑 | Jürgen Moll,Sebastian Carotta | 视频video | | 概述 | Includes cutting-edge techniques.Provides step-by-step detail essential for reproducible results.Contains key implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | This second edition book explores breakthrough technologies in the field of drug target identification and validation. The volume emphasizes particularly revolutionary technologies, such as CRISPR-related screening, “big data,” and .in silico. approaches, as well as .in vivo. applications of CRISPR and best uses of animal models in drug development. Written for the highly successful .Methods in Molecular Biology. series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. .Fully updated and authoritative, .Target Identification and Validation in Drug Discovery: Methods and Protocols, Second Edition. is an ideal guide for molecular and cellular biologists, pharmacologists, pathologists, bioinformaticians, clinical researchers, or investigators, as well as experts in other fieldsthat need a quick overview of these state-of-the-art technologies.. | 出版日期 | Book 2019Latest edition | 关键词 | Drug development; CRISPR technologies; Gene function; Animal models; Pharmacodynamics; Biomarkers; Pharmac | 版次 | 2 | doi | https://doi.org/10.1007/978-1-4939-9145-7 | isbn_ebook | 978-1-4939-9145-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 |
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