| 书目名称 | TGF-β in Human Disease | | 编辑 | Aristidis Moustakas,Keiji Miyazawa | | 视频video | | | 概述 | Covers the importance of TGF-ß in a wide spectrum of human diseases as no previously published book has done.Contains up-to-date scientific information written by world experts, reflecting the very ra | | 图书封面 |  | | 描述 | .Transforming growth factor-β (TGF-β) is a secreted polypeptide with multifunctional properties manifested during embryonic development, adult organ physiology, and pathobiology of major diseases, including cancer and fibrotic and cardiovascular diseases. The signaling pathway of TGF-β now is rather well understood. Continuing revelations in the mechanisms of action of TGF-β provide specific mechanistic examples of how human cells lose their controlled function and behave wrongly during the development of diverse diseases. Equally important, however, is the current promise of exploiting the TGF-β pathway in combating human disease. This book comprehensively covers major areas of human disease where the involvement of TGF-β is firmly established. Simultaneously, the book highlights major gaps in knowledge and the future directions of research that can benefit human medical science. The core set of diseases where TGF-β action is well documented and are included in the book are cancer and cardiovascular and fibrotic disorders. The central aim of the book is to stimulate young scientists to enter the prolific TGF-β field and find new solutions to the problems remaining in this area of | | 出版日期 | Book 2013 | | 关键词 | Cancer; Cardiovascular diseases; Fibrotic diseases; Inflammatory diseases; Transforming growth factor-β | | 版次 | 1 | | doi | https://doi.org/10.1007/978-4-431-54409-8 | | isbn_softcover | 978-4-431-54686-3 | | isbn_ebook | 978-4-431-54409-8 | | copyright | Springer Japan 2013 |
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发表于 2025-3-21 19:09:05
