书目名称 | Systems Biology of Metabolic and Signaling Networks | 副标题 | Energy, Mass and Inf | 编辑 | Miguel A. Aon,Valdur Saks,Uwe Schlattner | 视频video | | 概述 | Establishes the basis of a 21st century approach to biological complexity.Explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions.Broadens | 丛书名称 | Springer Series in Biophysics | 图书封面 |  | 描述 | .Systems Biology represents a new paradigm aiming at a whole-organism-level understanding of biological phenomena, emphasizing interconnections and functional interrelationships rather than component parts. The study of network properties, and how they control and regulate behavior from the cellular to organism level, constitutes a main focus of Systems Biology. This book addresses from a novel perspective a major unsolved biological problem: understanding how a cell works and what goes wrong in pathology. The task undertaken by the authors is in equal parts conceptual and methodological, integrative and analytical, experimental and theoretical, qualitative and quantitative, didactic and comprehensive. Essentially, they unravel the spatio-temporal unfolding of interacting mass-energy and information networks at the cellular and organ levels, as well as its modulation through activation or repression by signaling networks to produce a certain phenotype or (patho)physiological response. .Starting with the historical roots, in thirteen chapters this work explores the Systems Biology of signaling networks, cellular structures and fluxes, organ and microorganism functions. In doing so, | 出版日期 | Book 2014 | 关键词 | cell function; energy transfer; metabolic networks; signaling networks; systems biology; Proteomics; Metab | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-38505-6 | isbn_softcover | 978-3-662-50835-0 | isbn_ebook | 978-3-642-38505-6Series ISSN 0932-2353 Series E-ISSN 1868-2561 | issn_series | 0932-2353 | copyright | Springer-Verlag Berlin Heidelberg 2014 |
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