Titlebook: Systems Biology; Integrative Biology Aleš Prokop,Béla Csukás Book 2013 Springer Science+Business Media Dordrecht 2013 computational system

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Computational Infrastructures for Data and Knowledge Management in Systems Biologynities for Information technology (IT) departments. These increased demands have also led to increasing costs for IT infrastructure such as necessary computing power and storage devices, as well as further costs for manpower effort, required for maintenance. This chapter describes some of the challe

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Computational Tools and Resources for Integrative Modeling in Systems Biologynal tools that keep track of heterogeneous data of molecules and their interactions. Especially the integration of experimental data and pre-existing knowledge into computational models of biological systems is of considerable importance. . simulations of model behavior under similar conditions as i

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Agent-Based Modeling Approaches to Multi-Scale Systems Biology: An Example Agent-Based Model of Acutnt, population-based computational modeling method, is well suited to meeting this goal. By viewing systems as aggregates of populations of interacting components, agent-based models (ABMs) map well to biological conceptual models and present an intuitive means by which biomedical researchers can re

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Reconstruction and Comparison of Cellular Signaling Pathway Resources for the Systems-Level Analysis need uniform pathway definitions and curation rules applied to all pathways. Here, we compare KEGG, Reactome, Netpath and SignaLink pathway databases and examine their usefulness in systems-level analysis. Further on, we show that the integration of various bioinformatics databases allows a compreh

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Stéphane Ballereau,Enrico Glaab,Alexei Kolodkin,Amphun Chaiboonchoe,Maria Biryukov,Nikos Vlassis,Hasdeas in each paper. These ideas are interspersed with a brief survey of sparse matrix technology. An extensive unified bibliography is provided for the reader interested in more systematic information. The editors wish to thank Robert K. Brayton for his many helpful suggestions as chairman of the or

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Roberto Serra,Marco Villanideas in each paper. These ideas are interspersed with a brief survey of sparse matrix technology. An extensive unified bibliography is provided for the reader interested in more systematic information. The editors wish to thank Robert K. Brayton for his many helpful suggestions as chairman of the or

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Shinichi Kikuchi,Eberhard O. Voithe major ideas in each paper. These ideas are interspersed with a brief survey of sparse matrix technology. An extensive unified bibliography is provided for the reader interested in more systematic information. The editors wish to thank Robert K. Brayton for his many helpful suggestions as chairman of the or978-1-4615-8677-7978-1-4615-8675-3