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Titlebook: Synthetic Substrates in Clinical Blood Coagulation Assays; H. R. Lijnen,D. Collen,M. Verstraete Book 1980 Martinus Nijhoff Publishers bv,

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楼主: CHORD
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The Potential Use of Chromogenic Assays in the Routine Monitoring of Oral Anticoagulant Therapyon is gradually decreased until a maintenance dose is reached that result in the desired level of anticoagulation. In these so-called stabilized patients the administrations of the anticoagulant is such that the percentage of inhibition of the synthesis of procoagulant factors VII, II, IX and X is virtually the same for each factor (4).
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Antithrombin III and Factor Xa Determination in Patients with Low Dose Heparin and Hip Surgery patients undergoing total hip replacement. AT III levels were assayed by two different methods and heparin activity indirectly by the factor Xa inhibitor test as an agreement has still not been reached regarding the status of AT III concentration postoperatively (8–14).
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Advantages, Pitfalls, and Snags with Chromogenic Substrates aid of a spectrophotometer. This is a major new tool in the study of these enzymes. Like any new tool, it takes some time to become acquainted with its possibilities and limitations so that we can use it optimally. This communication will stress some of the more obvious pitfalls and snags that stan
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Automated Control of Coumarin Therapy by Chromogenic Factor X Assaythe prothrombin time or some similar test sensitive to deficiencies of factor II, VII and X. Such tests are not readily automated and rely on detecting fibrin clotting caused by thrombin. They are therefore affected by fibrinogen concentration and heparin as well as by coumarin induced defect. The p
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Antithrombin III and Factor Xa Determination in Patients with Low Dose Heparin and Hip Surgery low concentration of AT III requires a relatively high concentration of heparin to obtain an adequate anticoagulant effect. Due to minor prophylactic effects of low dose heparin (4–7), the AT III levels and heparin activity were determined to obtain further information on the thrombophilic state in
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Experiences with the Determination of Kallikrein, Plasminogen and Antiplasmin Using Chromogenic Subs and fibrinolysis by means of an automated enzyme analyzer. Especially for the laborious (and time consuming) determinations of fibrinolytic activities this development is very attractive and makes these determinations accessible for less specialized laboratories.
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