Titlebook: Synthetic Biology; From iGEM to the Art Manuel Porcar,Juli Peretó Book 2014 The Author(s) 2014 artificial life.biotechnology.metabolic engi

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Strategies for Making Life,omes, their chemical synthesis and transplantation into a cell chassis. In the long term, scientists hope to have genomic platforms to reinvent metabolic networks capable of producing molecules of biotechnological interest. On the other hand, a bottom-up strategy relies on the chemical implementatio

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The iGEM Competition,f heterodox, multidisciplinary and frontier work made by undergraduate students. We review the origin, organization and structure of the competition; we describe how an iGEM team can be set in place, and briefly summarize some of the main milestones and challenges of a competition that is only one d

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Are We Doing Synthetic Biology?,ring is still large and complex. Although synthetic biology is expected to rely on modelling and rational design, the fact is that synthetic constructs are still prone not to work as expected. This makes arguable the “genome writing” era some already claim we are at. Due to the incomplete knowledge

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Are We Doing Synthetic Biology?,of the complexity of the living we are not at the writing but only slightly ahead of the copying era. An analysis of the use of the term “synthetic biology” as well as the trends exhibited by the iGEM competition strongly suggests a more cautious use of synthetic metaphors.

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What Was Synthetic Biology?, than how to make a molecule?” Journalists have presented many advances in biology in the past century as an attempted synthesis of life. Nor is it new, therefore, the fine line which separates the scientific enthusiasm from hype.