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Titlebook: Synaptic Modifications and Memory; An Electrophysiologi Leon L. Voronin Book 1993 Springer-Verlag Berlin Heidelberg 1993 Gedächtnis.Hippoca

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楼主: finesse
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Excitatory Postsynaptic Potentials of Hippocampal Neurones and Their Low-Frequency Depression,he basic LTP mechanism is a persistent increase in the efficacy of excitatory synapses. Nevertheless, it was necessary to test this hypothesis more directly with intracellular recordings, including recordings of minimal PSPs (see Chap. 2). The hippocampus seemed to be a convenient structure for this
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Responses of Hippocampal Neurones During Long-Term Potentiation,ur experiments, long-term facilitation of hippocampal neuronal discharges had been described only after repeated (“chronic”) tetanic stimulations [161]. After we started our experiments, a few intracellular recordings from the DG neurones in vitro were published [252, 287]. Long-lasting changes (>90
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Models of Transmitter Depletion and Their Application to Analysis of Synaptic Plasticity (Literaturomings (Sect. 8.8) and make high demands on both sample sizes and their stationarity (Sects. 7.4.2, 8.6). In many cases, these conditions are difficult to satisfy because of technical difficulties and the plasticity of central neurones (e.g. Chap. 4). Therefore, a detailed analysis of other quantita
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Quantal Analysis of Hippocampal Long-Term Potentiation in Vivo,ry synapses (Chaps. 1–6) and, secondly, provide adequate statistical methods to study more precise localization of plasticity mechanisms in central synapses (Chaps. 7–11). Therefore, the quantal analysis of LTP appeared to become a real task. On the other hand, a decrease or even disappearance of IP
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Quantal Analysis of Minimal Postsynaptic Potentials in Hippocampal Slices: Binomial Model,not practical for studies of long-lasting events in neurones of vertebrate CNS. In fact, simultaneous recordings from two hippocampal neurones in our in vivo experiments [90] revealed UPSPs in only few cases (Sect. 12.3). Even under more stable conditions of recordings from hippocampal slices, the s
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