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Titlebook: Symposium in Immunology VII; Vaccination Martha M. Eibl,Christoph Huber,Ulrich Wahn Conference proceedings 1998 Springer-Verlag Berlin Heid

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Processing and Selection of Antigens by the Major Histocompatibility Complex Encoded Peptide Transpo9). A reliable method to predict which peptide from a given protein of interest could elicit a CTL response would thus be of great practical utility. A large body of data on molecular details of the peptide-HLA class I interaction has accumulated. By means of pool sequencing of naturally processed p
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DNA Vaccines for Infectious Diseases, Allergies and Cancere plasmid are expressed in the cells of the treated host. This extraordinarily simple approach has been translated into practice for many antigens from infectious agents, for putative tumor antigens, and for certain potential allergens. If the results currently obtained in animal models can be repli
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Strategies for Preventive and Therapeutic Vaccination Against Helicobacter pylori Infectioninfection approximately increases 1% per year of age and is about 40%–50% in the over-50-year-old population. However, in developing countries as much as 80% of the young population can be infected before adolescence, and nearly all elderly individuals are infected (M. 1994).
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Origin of Peptides Presented by MHC Class I Molecules: Generation by Proteasomes Precedes Evolution e thymus, in order to delete those that are self-reactive. A small proportion of MHC class I epitopes, derived from proteins of intracellular pathogens or from mutated tumor-associated self-proteins, are recognized by peripheral CD8 . T cells, which are then activated to cytotoxic cells and destroy the cells presenting these epitopes.
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Strategies for Immunomodulation and Evasion by Microbes: Important Consideration in the Development dly replicating microbes have to evade the primary defenses of the host and find another host prior to the development of specific secondary immune response, whereas the most successful parasites are those that can persist throughout the lifetime of the host.
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