Titlebook: Surgical Oncology Manual; Frances C. Wright,Jaime Escallon,Usmaan Hameed Book 20162nd edition University of Toronto General Surgery Oncolo

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Gallbladder Cancer,nvestigation for abdominal discomfort. T1a cancers are adequately treated with simple cholecystectomy. Radical cholecystectomy or extended right hepatectomy with portal lymphadenectomy is recommended for T1b and higher tumors. For all T stages with cystic duct involvement, bile duct resection to obt

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Desmoid Fibromatosis and Dermatofibrosarcoma Protuberans,y aggressive and in the case of DFSP, rarely metastasizing. Both tumors frequently contain specific mutations that may be useful in diagnosis or treatment with targeted therapies. The management of DF has recently changed from an approach of upfront surgical resection to an initial period of observa

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Gastric Adenocarcinoma,are observed in East Asian countries, where rates of gastric cancer are five- to tenfold the rates observed in Canada. In North America, the majority of patients diagnosed with gastric cancer have advanced disease at presentation. Surgical resection with appropriate lymphadenectomy remains the mains

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Gastrointestinal Stromal Tumours, mutations in the KIT (CD117) proto-oncogene or platelet-derived growth factor receptor alpha gene (PDGFRAa). They can arise in any location throughout the gastrointestinal tract but are found primarily in the stomach (60 %) and small intestine (30 %). Surgical resection is the cornerstone of manage

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fibroblast

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Merkel Cell Carcinoma, distant metastatic recurrence potential. They are found most commonly in Caucasian (94 %), elderly patients, with an average age at presentation being approximately 72 years. The most common sites of involvement include the head and neck (46–48 %), followed by the extremities (35–38 %), and trunk (

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Multidisciplinary Cancer Conferences,e that appropriate diagnosis and treatment options are considered prospectively. Common structural and functional elements including appropriate attendees are necessary to ensure a successful and well-structured MCC. Many studies have identified benefits of MCCs and MDCs which include, improved comp

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Neuroendocrine Tumors (GastroEnteroPancreatic),rease is likely explained by better detection, diagnosis, and classification. This chapter reviews the classification, grading, staging, and management of gastroenteropancreatic neuroendocrine tumors. Perioperative octreotide management and major clinical trials are explored.

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Non-melanoma Skin Cancer,s more common (80 % of non-melanoma skin cancers) than squamous cell carcinoma (SCC) (20 % of non-melanoma skin cancers), the incidence of both tumor types continues to rise despite growing awareness of the risk factors. BCC is characterized by local and sometimes disfiguring invasiveness; however,