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Titlebook: Surgical Oncology; A European Handbook Umberto Veronesi (Direttore Generale),Bo Arnesjø,F Book 1989 Springer-Verlag Berlin Heidelberg 1989

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Monoclonal Antibodies in the Diagnosis and Management of Colorectal Carcinomasd Freedman 1965) appears to remain the best marker of colorectal carcinomas for both types of applications, we shall illustrate this chapter with personal results obtained with MAbs directed against this antigen and only mention, by way of comparison, the progress made by the use of MAbs against different colorectal carcinoma markers.
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Chemotherapy in Cancer Treatmentchemotherapy is unquestionable, with long-term disease-free survival (cure) in more than 50% of patients with acute lymphocytic leukemia, Hodgkin’s disease or aggressive types of non-Hodgkin’s lymphoma and in smaller percentages of patients with acute nonlymphocytic leukemia and indolent types of non-Hodgkin’s lymphoma (Chabner et al. 1984).
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Intraoperative Radiotherapyt normal tissues, thereby increasing the local control rate without increasing the complication rate. The delivery of tumoricidal doses of radiation with external beam techniques, especially the treatment of intra-abdominal, retroperitoneal, or pelvic malignancies, can be accompagnied by a short- or long-term toxicity to normal tissues.
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The Biologic Basis of Cancer Chemotherapydrugs are used have evolved empirically over the last four decades, our understanding of the biologic principles underlying cancer chemotherapy has increased as well, providing the foundation for more effective cancer treatment in the future.
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