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Titlebook: Supramolecular Structure and Function 9; Greta Pifat-Mrzljak Book 2007 Springer Science+Business Media B.V. 2007 FTIR.Microarray.biology.b

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Protein Complexes in SUMO Signaling,d apoptosis. Here we describe details of the SUMO molecular machineries implicated in the formation of signaling networks that underlie the specificity in these biological processes. SUMO signaling is also altered during development of human diseases, including cancer pathogenesis, and these alterat
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Mass Spectrometry and Glycomics,romolecules, like proteins and nucleic acids. MS, as an universal and indispensible tool for analysis of biological samples after introduction of soft ionization techniques, like Fast Atom Bombardment (FAB), electrospray (ESI) and matrix-assisted laser desorption ionization (MALDI), allows a high de
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Mechanisms of Supramolecular Assembly Exemplified by Microtubules and Amyloid Fibril Formation,ral information on many individual proteins and their complexes. In cases where such proteins form biological polymers, this information provides a firm basis for consideration of structural factors affecting supramolecular assembly. However information from additional sources and techniques is freq
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Hepatitis B Virus (HBV): The Life-cycle and Assembly of a Complex Virus,nto the cell, transport of the partially-double stranded viral DNA to the nucleus, its uncoating and “repair” by cellular polymerases to produce the covalently-closed circular DNA. Transcription and translation of the viral genes, by cellular factors, is discussed, together with the roles of the vir
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Photo-oxidative Stress in the Presence of a Water-soluble Derivative of C60: ESR and AFM Assays,m, where maintaining the redox equilibrium is a prerequisite for normal functioning. Under certain conditions, however, ROS can damage important parts of cells, including proteins, membranes and DNA. At the cellular level, such pathogenic scenario, also called oxidative stress (OS), results from an
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Virtual Ligand Screening: A Method to Discover New Drug Leads,rticular target receptor under consideration on the computer. Key prerequisite is the knowledge about the spatial and energetic criteria responsible for protein-ligand binding. The concepts and prerequisites to perform VS are summarized, given limitations are analyzes and explanations are sought for
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