Titlebook: Supporting Real Time Decision-Making; The Role of Context Frada Burstein,Patrick Brézillon,Arkady Zaslavsky Book 2011 The Editor(s) (if ap

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tibility regions have been suggested from genetic studies by employing either genome-wide or candidate gene approaches. Because of the lack of a linear correlation between the presence of risk genes and the onset of disease, the exact susceptibility genes encoded in these regions remain largely elus

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Murray Turoff,Connie White,Linda Plotnickrocess that is critical for cell growth and survival.No othe.Over a decade ago, a small cellular protein of 12 kDa, with 18% homology to the well-known ubiquitin protein, was co-discovered and termed Small Ubiquitin-like Modifier, or SUMO. Sumoylation is a post-translational modification that utiliz

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Linda Plotnick,Murray Turoff,Connie Whiteability in eukaryotic cells. The ubiquitin conjugation system regulates the stability of a myriad of vital cellular proteins in a signal-dependent manner by targeting them for destruction via the proteasome-mediated degradation pathway. Recent research efforts have unveiled an evolutionarily conserv

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Fergal Carton,Frederic Adam,Patrick Brézillond in mutants of the SUMO conjugation and deconjugation enzymes reflect these essential roles, and detailed analyses of these mutants under different growth conditions revealed roles in biotic and abiotic stress responses, phosphate starvation, nitrate and sulphur metabolism, freezing and drought tol

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Robert Baksa,Murray Turoffrelate with decreased transcriptional activity, and in many cases modulation of the chromatin template is implicated. Sumoylation of the core histones is associated with transcriptional silencing, and transcription factor sumoylation can decrease gene expression by promoting recruitment of chromatin

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Yves Vanrompay,Yolande Berbersiration..".Ken Oringer, internationally renowned and award-winning chef.Clio Restaurant, Uni Sashimi Bar, Boston.".Congratulations on writing such an aesthetically beautiful, informative and inspiring book. ... I shall not hesitate to recommend your book to those colleagues, who like me, are fascina

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