Titlebook: Suicide Gene Therapy; Methods and Protocol Nejat Düzgüneş Book 2019 Springer Science+Business Media, LLC, part of Springer Nature 2019 Canc

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Stress-Fracture

interlude

Extracellular Vesicles as Carriers of Suicide mRNA and/or Protein in Cancer Therapy,erapy can used as a form of cancer treatment. A particularly attractive paradigm in this regard involves the selective introduction of transgenes into cancer cells that converts inactive prodrugs into active chemotherapeutic agents, thereby triggering the death of cancer cells. Since prodrugs are in

Brittle

Cabg318

,Resveratrol-Responsive CArG Elements from the Egr-1 Promoter for the Induction of GADD45α to Arrestnto a lethal drug, or to produce a cytotoxic effect. We have constructed a suicide gene therapy vector that contains resveratrol-responsive CArG elements from the Egr-1 promoter and the GADD45α open reading frame. CArG elements are utilized as a “molecular switch” to drive the expression of GADD45α.

厚颜

CLAN

In Vitro Assay for the Evaluation of Cytotoxic Effects Provided by a Combination of Suicide and Kil genes. For this purpose, an approach can be applied based on the transient transfection of cultured human cells with a specifically designed set of mono- and bicistronic expression constructs and on the comparison of their cytotoxic effects. Here the application of this approach is described using

buoyant

Engineered Thymidine-Active Deoxycytidine Kinase for Bystander Killing of Malignant Cells, apoptosis or are capable of directly inducing apoptosis. Suicide gene therapy of cancer (SGTC) involves the targeted or localized delivery of suicide transgene sequences into tumor cells by means of various gene delivery vehicles. SGTC that operates via the potentiation of small-molecule pharmacolo

rheumatology

会议