书目名称 | Subtilisin Enzymes |
副标题 | Practical Protein En |
编辑 | Richard Bott,Christian Betzel |
视频video | |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | Subtilisin is the most extensively studied model system for protein engineering. The primary motivating factor for the interest in subtilisin is the commercial utility of this class of proteases. The subtilisin symposium was the first international meeting to bring together a large number of groups that have focused on the subtilisins and the subtilases-the protein superfamily of subtilisin-like enzymes. The results presented at the symposium are in this way a unique compendium of a broad spectrum of work largely focused on harnessing the potential of site-directed mutagenesis to understand and deliberately alter the function of these enzymes toward a desired end. This sort of protein engineering has been extremely successful in subtilisin, with many such "engineered" enzymes now widely used in commer cial enterprises. In this regard the experience derived from subtilisin does represent practical protein engineering. It is becoming clear that subtilisin represents a larger class of enzymes, the subtilases, that include many of the human pro hormone-converting enzymes. As international collabo rative efforts to sequence entire genomes continue, we can reasonably expect that additi |
出版日期 | Book 1996 |
关键词 | enzyme; enzymes; fungi; genes; protein; protein engineering; system |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4613-0319-0 |
isbn_softcover | 978-1-4613-7995-9 |
isbn_ebook | 978-1-4613-0319-0Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines |