| 书目名称 | Study of the Peptide-Peptide and Peptide-Protein Interactions and Their Applications in Cell Imaging |
| 编辑 | Jianpeng Wang |
| 视频video | http://file.papertrans.cn/882/881075/881075.mp4 |
| 概述 | Nominated by the Chinese University of Hong Kong as an outstanding Ph.D. thesis.Systematically elucidates a self-developed labeling method of covalent protein conjugation.Reports a novel anti-fungus p |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | .This thesis focuses on the study of interactions between protein and peptides and their potential applications in cell imaging and nanoparticle surface modification. Drawing inspiration from naturally occurring coiled-coil binding pairs, it proposes a novel covalent peptide tag and probe system, based on the concept of “affinity guided covalent conjugation.” This newly established methodology provides complementary resolution to protein labeling, imaging and trafficking. By systematically investigating the coordination interaction between protein and quantum dots using various engineered protein ligands, this thesis proposes a general rule for protein self-assembly on the surface of quantum dots and reports a revolutionized nanobelt protein in accordance with this rule. It is an extraordinary example of interdisciplinary research, providing answers to real-life biological problems from a chemistry perspective.. |
| 出版日期 | Book 2016 |
| 关键词 | Coiled-coil interaction; Covalent protein conjugation; Peptide tag; Protein folding; Protein self-assemb |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-662-53399-4 |
| isbn_softcover | 978-3-662-57134-7 |
| isbn_ebook | 978-3-662-53399-4Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer-Verlag Berlin Heidelberg 2016 |
|Archiver|手机版|小黑屋|
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