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Titlebook: Structure-Based Drug Design; Experimental and Com Penelope W. Codding Book 1998 Springer Science+Business Media Dordrecht 1998 Amino acid.b

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书目名称Structure-Based Drug Design
副标题Experimental and Com
编辑Penelope W. Codding
视频video
丛书名称NATO Science Series E:
图书封面Titlebook: Structure-Based Drug Design; Experimental and Com Penelope W. Codding Book 1998 Springer Science+Business Media Dordrecht 1998 Amino acid.b
描述.Structure-Based Drug Design. brings together scientistsworking on different aspects of the subject, demonstrating thenecessary collaboration and interdisciplinary approach to this complexarea. The focus is on X-ray crystallographic and computationalapproaches. The general aspects of these approaches are introduced inthe first six articles. The remaining articles provide examples of theapplication of X-ray crystallography, molecular modelling, moleculardynamics, QSAR, database analysis, and homology modelling. The paperscover a wealth of interesting problems in the design of new andenhanced pharmaceuticals.
出版日期Book 1998
关键词Amino acid; base; drug design; molecular modelling; pharmaceuticals; protein; receptor
版次1
doihttps://doi.org/10.1007/978-94-015-9028-0
isbn_softcover978-90-481-5078-6
isbn_ebook978-94-015-9028-0Series ISSN 0168-132X
issn_series 0168-132X
copyrightSpringer Science+Business Media Dordrecht 1998
The information of publication is updating

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Structure, Mechanism of Action and Inhibition of Dehydrogenase Enzymes,the addition of dozens of new members to the SDR family they are seen to vary in total length from 240 to 360 residues overlapping the length of the LCDH’s. Although the two families have no sequence similarity they share common characteristics. Members of both families use NAD(H) and/or NADP(H) as
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In Search of Hypoglycaemic Agents for the Treatment of Non-Insulin Dependent Diabetes Mellitus,rabbit muscle glycogen phosphorylase (GP) as a model for the structure-based design of potent inhibitors which may prove useful for the treatment of non-insulin dependent (Type II) diabetes mellitus (NIDDM). Physiological studies have shown that one of these compounds (N-acetyl-β-D-glucopyranosylami
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