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Titlebook: Structure and Function of Gangliosides; Lars Svennerholm,Paul Mandel,Paul-Francis Urban Book 1980 The Editor(s) (if applicable) and The Au

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Brain and Retinal Ganglioside Composition from Different Species Determined by TLC and HPTLCRGAN, 1972). In establishing the physiological role of gangliosides, their distribution in different brain areas, cell types, and subcellular fractions should be useful. The presence of a high amount of gangliosides in plasma membranes and in synaptic junctions has been established (HAMBERGER and SV
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Gangliosides of the CNS Myelin Membrane concentration, which in the case of rat amounts to about one-tenth that in synaptic plasma membranes. This may account for the fact that when first detected in isolated myelin. they were believed to represent neuronal contamination. Subsequent studies of Suzuki and coworkers. provided strong if not
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Gangliosides in Fish Brainpecially taking into account ganglioside localization. In our studies of vertebrate brain gangliosides, the most detailed study was done on fish brain. The fishes are extremely numerous group diverse in their habitats, mode of life and level of development of the nervous system.
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Glycolipids and Cell Differentiationhesis of collagen by bone fibroblasts (MANNER and KULEBA, 1974) or tendon cells (SCHWARTZ .., 1976). However, differentiation is sometimes characterized by a net change in the cell morphology which accompanies the biochemical changes as for example with myoblasts.
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Enzymic Degradation of Gangliosidesffer, as they may severely affect enzyme activity. It is also very important to realize that O-acetylated or O-methylated glycons are often resistant to glycosidases. Finally, one should bear in mind that the glycosidases used may be contaminated with one or several unexpected enzyme activities.
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