| 书目名称 | Structural and Functional Organization of the Synapse | | 编辑 | Johannes W. Hell,Michael D. Ehlers | | 视频video | | | 概述 | Deals directly with the different and specific aspects of synaptic function, unlike other available books which cover the fundamentals.Includes supplementary material: | | 图书封面 |  | | 描述 | The synapse is a fascinating structure for many reasons. Biologically, it is an exquisitely organized subcellular compartment that has a remarkable capacity for fidelity and endurance. Computationally, synapses play a central role in signal transmission and processing that represent evolution’s solution to learning and memory. Nervous systems, including our own brains, possess an extraordinary capacity for adaptation and memory because the synapse, not the neuron, constitutes the basic unit for information storage. Because the molecular complexities underlying signal processing and information storage must occur within the tiny space of the synapse, the precise molecular organization of proteins, lipids, and membranes at the synapse is paramount. Given the central role of the synapse in neuronal communication, it comes as no surprise that dysregulation of the synapse accounts for many, if not most, neurological and psychiatric disorders. Clinically, the synapse thus constitutes a primetarget for treatments of these diseases. It is for these reasons that we have chosen to focus our work on deciphering the structural and functional organization of the synapse. We have assembled leade | | 出版日期 | Book 2008 | | 关键词 | Alzheimer; biochemistry; neurology; neurons; physiology | | 版次 | 1 | | doi | https://doi.org/10.1007/978-0-387-77232-5 | | isbn_softcover | 978-1-4899-7905-6 | | isbn_ebook | 978-0-387-77232-5 | | copyright | Springer-Verlag US 2008 |
The information of publication is updating
|
|
发表于 2025-3-21 19:19:36
