Titlebook: Stress Challenges and Immunity in Space; From Mechanisms to M Alexander Choukèr Book 2020Latest edition Springer Nature Switzerland AG 2020

Flatter

Endocannabinoids, “New-Old” Mediators of Stress HomeostasisIn contrast to its long biologic history, the scientific record of the ECS is very short. Whereas the occurrence of genes for the endocannabinoid receptors has been described in ancient animals reaching at least as far back as the predecessor of tetrapods (amphibians reptiles, birds, and mammals), m

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Immune System in Space: General Introduction and Observations on Stress-Sensitive Regulationsng flight, where landing and readaptation are significant stressors. More recent data, particularly studies onboard ISS, indicate that this phenomenon persists for the duration of a 6-month orbital spaceflight. Persistent decrements in the function of specific innate or adaptive immune cells, or alt

persistence

Innate Immunity Under the Exposome of Space Flightns, is present in all life and the result of long years of adaptation to the environment. A fast, less-specific reply to microbial threats using cellular and humoral components without the build-up of an immunological memory are its features. As we progress exploring the universe, manned space missi

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Choreography

Adaptive Immunity and Spaceflights have also confirmed that to some degree immunity is compromised . spaceflight. A comprehensive understanding of the nature of these immune changes is lacking. This chapter reviews the current evidence regarding spaceflight effects on the function of the adaptive immune system, and speculates on po

Occlusion

B-Cell Immunology in Spacepetence. This chapter will review known effects on B-cell development and on the response of these antibody-producing cells under real or simulated space conditions. Comparison of changes affecting these cells with those previously reported in the elderly suggests that space missions could lead to p

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Stress, Hypoxia, and Immune Responsesr mechanisms known to induce immune imbalance and suppression as described in this book, this chapter focuses on the still very little known role of hypoxia-triggered immunosuppressive mechanisms in astronauts/cosmonauts e.g. during long-duration space missions. Such hypoxia signaling-dependent path

Feature

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Entering a New Era of Holistic Research in Establishing Groundwork for Future Human Space Exploratio to space” to moon again and to Mars, following the first era in exploring the Earth orbit and the landing on the Moon in the past century. These new strategies mandate that we also need to enter a new era of holistic research to better understand human beings subjected to extreme environments for longer periods of time.

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